Martina Accursi
ETH Zürich
Advancing Healthcare Applications: MOF and COF-Integrated Magnetic Micro/Nanorobots for Precision Drug Delivery
Supervisor: Prof. Salvador Pané Vidal
Personal Introduction
Martina completed both her bachelor’s and master’s degrees at Politecnico di Milano in Biomedical Engineering, with a focus on tissue engineering. Her academic path culminated in a thesis abroad at King’s College London, where she developed a custom perfusion bioreactor to investigate immune-ECM interactions in liver fibrosis. In May 2025, she began her PhD within the GREENS Doctoral Network at ETH’s Multiscale Robotics Lab, where she is working on MOF- and COF-integrated magnetic micro/nanorobots for precision drug delivery, leveraging magnetic navigation systems for accurate manipulation in 3D space and targeted therapeutic action.
On a personal note, she is a cheerful person and is driven by curiosity and problem-solving. She simply cannot move forward until she has solved the challenge in front of her.
Project Introduction
Effective integration of MOFs and COFs with magnetic micro/nanorobotic structures to enhance their capability for targeted drug delivery applications, as well as addressing its optimization for biodegradability and magnetic control to ensure that the integrated systems are not only biodegradable but also retain efficient magnetic manipulation capabilities for precise drug delivery. The corresponding in vitro and ex vivo evaluation will be conducted to assess the efficacy of drug encapsulation, release kinetics, and navigability of these integrated systems in simulated biological environments.